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You are here: Home / Journal Club / NICE on Bronchiolitis: Less is More!

NICE on Bronchiolitis: Less is More!

November 21, 2016 By John Gilbert Leave a Comment

niceAs the nights get longer and the weather gets cooler emergency departments across the UK will see an increase in unwell children.

The vast majority will have a self-limiting illness and can be safely discharged with appropriate safety netting. The emergency clinician’s role is crucial in identifying the children that require an in-patient stay.

Infants with cough, increased work of breathing and a fever are going to start pouring in. ‘Tis the season to be bronchiolitic.

What is bronchiolitis?

Bronchiolitis is characterised by inflammation of the small airways (bronchi and bronchioles) caused by a viral pathogen – most commonly respiratory syncytial virus. It is a disease of the under 2s, and virtually all kids will get it.

Oedema and excess mucous production reduce the diameter of the small airways. This presents clinically with a cough, coryzal symptoms and increased work of breathing to maintain ventilation. Auscultation of the lungs will often demonstrate a wheeze and transmitted upper airway sounds.

Reduced oral intake and dehydration are a feature of more severe cases, as are apnoeic episodes.

bronchiolitis

Last year, NICE released updated guidance on how to manage bronchiolitis (1). Much of this relates directly to who can be discharged from ED/short stay wards, and who requires admission.

Diagnosing bronchiolitis

The child must be under 2, though it’s most common between 3-6 months.

The worst symptoms are normally between day 3 and 5. The cough is the longest symptom to resolve, and that takes less than 3 weeks in 90% of ‘bronchs’.

Criteria for formal diagnosis:

  • Initial coryzal prodrome lasting 1-3 days
  • Persistent cough
  • Tachypnoea or chest wall recessions (or both)
  • Wheeze or crackles bilaterally (or both)

Important additional points to consider:

  • Low-grade fever and poor feeding are common
  • Apnoea can be the only clinical sign in infants less than 6 weeks old.
  • Features pointing to the alternative diagnosis of pneumonia:
    • Fever >39 degrees
    • Persistent unilateral signs on chest examination

Who should we admit?

This depends on two features of the case: clinical features of the episode and underlying co-morbidities. 

Worrying clinical features that warrant an admission:

  • Apnoeic episodes
  • Persistent oxygen saturation of less than 92% when breathing air
  • 50–75% of usual oral intake
  • Persisting severe respiratory distress (e.g. grunting, marked chest recession, or a respiratory rate >70)

If any of the following co-morbidities are present the child is high risk for severe deterioration; urgent discussion with paediatrics is indicated even if the child seems relatively well: 

  • Chronic lung disease
  • Congenital heart disease
  • Under 3 months
  • Prematurity, particularly under 32 weeks
  • Neuromuscular disorders
  • Immunodeficiency

What NOT to do

Bronchiolitis should be diagnosed on clinical grounds. Routine bloods, a chest X-ray and blood gas testing are not recommended.

Capillary blood testing should only be considered in severe cases – when supplemental oxygen concentration is greater than 50%.

Routine nasal airway suctioning is only recommended in kids who are suffering from apnoeic episodes.

There is no evidence that any of the following work in bronchiolitis, regardless of severity:

  • Antibiotics
  • Steroids (inhaled or systemic)
  • Montelukast
  • Nebulisers:
    • Hypertonic saline
    • Adrenaline
    • Salbutamol
    • Ipratropium

That’s right… NO NEBS!

So, what should you do in the ED?

The management of bronchiolitis can be summed up in 3 words: Less is more. Avoid unnecessary and potentially harmful treatment and investigations in these little ones.

Clear and careful parental reassurance is easily the most important intervention in the overwhelming majority. Keeping these kids hydrated and fed is crucial, and so often it’s safer for them to be managed at home.

Having said that, don’t forget the following:

  • Supplemental oxygen should be given if saturations are less than 92%*.
  • Give supplemental feeding via nasogastric tube if they’re not tolerating anything orally.
  • Apnoea? Consider suction of upper airways.

*There is no firm consensus across international guidelines amongst what oxygen saturation level is appropriate. An interesting recent trial published in the Lancet (currently open access) showed no change in length of symptoms with a target saturation of 90% (2).

The really sick ones need CPAP

When kids have impending respiratory failure, they show signs of exhaustion (‘listlessness’, feeble respiratory effort), have recurrent apnoeas, and fail to maintain saturations despite high flow oxygen therapy.

A trial of CPAP should be commenced. It goes without saying that these cases require immediate senior paediatric involvement.

However, bronchiolitis kids that need CPAP are exceedingly rare. Phew.

I’ll leave you with this…

The art of medicine consists of amusing the patient while nature cures the disease.

Voltaire (1694-1778)

References

  1. NICE Guideline – Bronchiolitis in children: diagnosis and management, June 2015
  2. BIDS trial

#FOAMed links

Fellow Pondering EM blogger @PEM geek has put together a great review

DFTB on bronchiolitis 

Damien Roland’s approach to bronchiolitis

Why bronchodilators don’t work

Cliff Reid on bronchodilators

 

John
@johnnyg1986

Filed Under: Journal Club, Pondering Paeds Tagged With: Bronch, Bronchiolitis, NICE guideline, Paeds

Authors

  • Adam Walker
  • Andrew Wilkinson
  • John Gilbert
  • Pondering EM

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